What if Cancer Simply Can’t Be Cured?

By Published on November 17, 2015

A new study raises a sobering possibility: that cancer may simply be here to stay. Researchers at Kiel University, the Catholic University of Croatia and other institutions discovered that hydra — tiny, coral-like polyps that emerged hundreds of millions of years ago — form tumors similar to those found in humans. Which suggests that our cells’ ability to develop cancer is “an intrinsic property” that’s evolved at least since then — way, way, way before we rallied our forces to try to tackle it, said Thomas Bosch, an evolutionary biologist at Kiel University who led the study, published in Nature Communications in June 2014.

To get ahead of cancer, he said, “you have to interfere with fundamental pathways. It’s a web of interactions,” he said, adding that it’s very difficult to do. That’s why we’ll most likely “never get rid of” our potential to develop cancer.” Cancer results from DNA mutations that throw a wrench into the molecular circuits that regulate the cell cycle. Unregulated, cancer cells multiply uncontrollably. They also evade a process known as apoptosis, in which cells with genetic mistakes essentially commit suicide.

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