The United States said on Tuesday it was disturbed by anti-U.S. hostility voiced by Iran’s top leader after a nuclear deal, as both countries’ top diplomats sought to calm opposition to the accord from hardliners at home.

U.S. Secretary of State John Kerry said a speech by Iranian Supreme Leader Ali Khamenei on Saturday vowing to defy American policies in the region despite a deal with world powers over Tehran’s nuclear program was “very troubling.”

“I don’t know how to interpret it at this point in time, except to take it at face value, that that’s his policy,” he said in the interview with Saudi-owned Al Arabiya television.

Read the article “U.S. ‘Disturbed’ by Iranian Leader’s Criticism after Deal” on reuters.com.