In this exclusive interview with Father Matt Malone, S.J., editor in chief of America, Vice President Joseph R. Biden, Jr. discusses his thoughts on Pope Francis, as well as his Catholic faith, his upbringing, his public life and private sorrow, and his thinking about a possible presidential campaign. The interview was conducted on September 17, 2015 in Washington, D.C. Mr. Biden refers in the full interview, below, to Father Malone’s published account of the death of his brother in an automobile accident in 1984.